منابع مشابه
α-Linolenic acid, linoleic acid and heart failure in women.
α-Linolenic acid (18 : 3n-3) intake and linoleic acid (18 : 2n-6) intake have been associated with lower rates of CHD, though results have not been consistent. The relationship of these fatty acids with incident heart failure (HF) is not well established. We examined the hypothesis that women with higher intakes of 18 : 3n-3 and 18 : 2n-6 would have lower rates of HF hospitalisation and mortali...
متن کامل-Linolenic acid and cardiovascular disease
Oomen et al (1) reported on the lack of association between -linolenic acid (ALA, 18:3n 3) consumption and the incidence of coronary artery disease in a 10-y follow-up. We believe that 2 major limitations of this study might have affected its outcome and led to the wrong conclusions. First, this study did not control for plasma concentrations of -linolenic acid; it is thus difficult to establis...
متن کاملThe evidence for α-linolenic acid and cardiovascular disease benefits: Comparisons with eicosapentaenoic acid and docosahexaenoic acid.
Our understanding of the cardiovascular disease (CVD) benefits of α-linolenic acid (ALA, 18:3n-3) has advanced markedly during the past decade. It is now evident that ALA benefits CVD risk. The expansion of the ALA evidence base has occurred in parallel with ongoing research on eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) and CVD. The available evidence enables c...
متن کاملOleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes.
BACKGROUND Oleic acid is the principal fatty acid of olive oil composition and is reported to play a crucial role in its healthy aspects. However, the detailed mechanism of action is poorly understood. AIMS This study aims to elucidate the role of oleic acid in calcium signaling in rat thymocytes, in comparison to linoleic and linolenic acid. METHODS Fatty acids were applied to thymocytes i...
متن کاملDietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease.
BACKGROUND n-3 (omega-3) PUFA has been proposed as having health-promoting effects, primarily in relation to ischemic heart disease (IHD). Whether these benefits can be achieved by both α-linolenic acid (ALA, 18:3n-3) and n-3 long-chain PUFA (LC-PUFA) is debatable. OBJECTIVE The objective was to examine the association between ALA intake and risk of IHD in healthy subjects and to see if this ...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 1999
ISSN: 0002-9165,1938-3207
DOI: 10.1093/ajcn/69.5.827